Location: Melbourne, VIC, AU
Company: CSIRO
Acknowledgement of Country
CSIRO acknowledges the Traditional Owners of the land, sea and waters, of the area that we live and work on across Australia. We acknowledge their continuing connection to their culture and pay our respects to their Elders past and present. View our vision towards reconciliation
Child Safety
CSIRO is committed to the safety and wellbeing of all children and young people involved in our activities and programs. View our Child Safe Policy.
The Opportunity
- Bring your expertise in fermentation unit operations to build internal capabilities.
- Indefinite full-time opportunity within a start up team.
- Join CSIRO - Australia's leading scientific research organisation.
CSIRO’s Manufacturing Business Unit brings together multi-disciplinary scientific and engineering capabilities using world-class infrastructure to partner with industry in order to develop innovative products and processes to allow Australian manufacturers to be globally competitive and environmentally sustainable. CSIRO is embarking on an exciting strategy to expand capability in manufacture of vaccines and therapeutics in prokaryotic hosts. This is an opportunity to be part of the start-up team.
We are looking for a highly motivated Research Scientist – Regulated Biomanufacturing Fermentation Lead to join the Upstream Operations, Regulated Biomanufacturing team accountable for providing advanced manufacturing scientific knowledge in the discipline of microbiology, fermentation, and associated bioprocessing and lead in securing of projects, as well as facilitating the transfer and execution of new fermentation protocols into the Regulated Biomanufacturing laboratories. If you are a team player , an experienced scientific leader, and hold extensive client engagement experience, then do not hesitate to apply.
Your duties will include:
- Leading fermentation unit operations for expression of recombinant proteins in a regulated manufacturing setting -
- Leading and ensuring that new manufacturing protocols are established in accord with the CSIRO Quality Management System and are completed within the agreed timeframes and budget.
- Identifying opportunities for continuous improvement in the operation of fermentation and bioprocessing systems.
- Assuming ownership of fermentation equipment and maintaining the same equipment in a compliant and ready state for ongoing manufacturing operations.
- Accurately writing and reviewing regulated batch manufacturing records and communicating research results to clients and the scientific community.
- Engaging with clients on fermentation protocols for a range of host expression systems to secure projects for execution in the microbial production laboratories.
- Participate in project scoping, planning, and budgeting activities that shape the future direction of the fermentation /mRNA manufacturing discipline.
- Acting as a trusted advisor, utilising knowledge of client’s business and understanding of their underlying needs.
Location: Clayton, VIC
Salary: *AU$121k - AU$161k plus up to 15.4% superannuation
Tenure: Indefinite / full-time
Reference: 94871
* Applications are invited across two capability levels (CSOF6 or CSOF7) and the successful candidate will be appointed at the level that is commensurate with their skills and experience. Refer to the attached position description below for additional duties at higher capability level.
To be considered you will need:
Essential
- An advanced degree in Microbiology, Biotechnology, Biochemical Engineering or related field or equivalent experience.
- Demonstrated experience in the development and application of fermentation protocols for the manufacture of biotherapeutic proteins and vaccine antigens.
- Theoretical and practical knowledge of fermentation unit operations including process development, optimisation, transfer, and troubleshooting.
- Prior experience working under the framework for Good Manufacturing Practices (GMP) gained through industrial experience.
Desirable
- Knowledge of midstream unit operations for isolation and purification for both secreted and intracellular recombinant protein products.
- Direct experience and working knowledge of current GMP frameworks for manufacture of human vaccines and biotherapeutics with global regulators such as the Therapeutic Goods Administration, US Food and Drug Administration, or European Medicines Authority.
- Experience in scoping, securing and delivering fermentation projects.
- Experience with E. Coli and Pichia fermentation and mRNA manufacturing processes highly regarded.
For full details about this role please review the Position Description.
Eligibility
Applications for this position are open to Australian/New Zealand Citizens or Australian Permanent Residents. Appointment to this role is subject to provision of a national police check and may be subject to other security/medical/character requirements.
Flexible Working Arrangements
We work flexibly at CSIRO, offering a range of options for how, when and where you work.
Diversity and Inclusion
We are working hard to recruit people representing the diversity across our society, and ensure that all our people feel supported to do their best work and feel empowered to let their ideas flourish.
About CSIRO
At CSIRO Australia's national science agency, we solve the greatest challenges through innovative science and technology. We put the safety and wellbeing of our people above all else and earn trust everywhere because we only deal in facts. We collaborate widely and generously and deliver solutions with real impact.
CSIRO is committed to values-based leadership to inspire performance and unlock the potential of our people.
CSIRO is committed to the safety and wellbeing of all children and young people involved in our activities and programs, whether we are undertaking research, engaging with the public or nurturing future scientists in person or online. Source – CSIRO Child Safe policy 2023
Join us and start creating tomorrow today!
How to Apply
Please apply on-line and provide a cover letter and CV that best demonstrate your motivation and ability to meet the requirements of this role.
Applications Close
30 November 2023, 11:00pm AEDT